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- Contents -

I. Normal Renal Function: Molecular, Cellular, Structural, and Physiologic Principles
1. Embryology and Maturation – Susan Quaggin
2. Anatomy and Topography – Kirsten Madsen
3. Cell Biology – Pierre Ronco/Gerard Friedlander
4. Hemodynamics – Lance D. Dworkin
5. Metabolic Basis of Solute Transport – Bruce C. Kone
6. Transport of Inorganic Solutes – David B. Mount
7. Transport of Organic Solutes – Orson Moe
8. Renal Acidification – Lee L. Hamm
9. Cell Biology of Vasopressin Action – Dennis Brown
10. Urine Concentration and Dilution – Mark A. Knepper

II. Integrated Control of Body Fluid Volume and Composition
11. Vasoactive Peptides and the Kidney – Mark E. Cooper/Karin Jandeleit-Dahm
12. Arachidonate Metabolites – Raymond C. Harris
13. Extracellular Fluid and Edema Formation – Karl L. Skorecki
14. Disorders of Water Balance – Tomas Berl
15. Disorders of Acid-Base Balance – Thomas D. DuBose
16. Disorders of Potassium Balance – David B. Mount
17. Disorders of Calcium, Magnesium, and Phosphate Balance – Kevin Martin

III. Epidemiology and Risk Factors in Kidney Disease
18. Epidemiology of Kidney Disease – Josef Coresh
19. Risk Factors and Kidney Disease – A. Levey/ V. Menon/M. Sarnak
20. Nephron Endowment – Valerie Luyckx/Barry Brenner
21. Gender and Kidney Disease – Joel Neugarten
22. Aging and Kidney Disease – Moshe Levi

IV. Evaluation of the Patient with Kidney Disease
23. Approach to the Patient with Kidney Disease – Robert Toto
24. Laboratory Assessment of Kidney Disease – Bertram L. Kaiske
25. Interpretation of Urine Electrolyte and Acid-Base Parameters – Mitchell Halperin
26. Adaptation to Nephron Loss – Maarten Taal/Barry Brenner
27. Renal and Systemic Manifestations of Glomerular Disease – Sharon Anderson
28. Diagnostic Kidney Imaging – William D. Boswell
29. Interventional Nephrology – David Warnock

V. Disorders of Kidney Function
30. Acute Renal Failure – Michael Clarkson
31. Primary Glomerular Disease – Ronald Falk
32. Secondary Glomerular Disease – Gerald Appel
33. Micro and Macrovascular Diseases of the Kidney – Kamal F. Badr
34. Tubulointerstitial Diseases – Giuseppe Remuzzi/Marc E. de Broe/Noberto Perico
35. Urinary Tract Infection, Pylonephritis, and Reflux Nephropathy – Nina E. Tolkoff-Rubin/ Robert Rubin
36. Urinary Tract Obstruction – Mark L. Zeidel
37. Diabetic Nephropathy – Hans-Henrik Parving
38. Nephrolithiasis – David Bushinsky
39. Renal Neoplasia – Michael Atkins

VI. Genetic Basis of Kidney Disease
40. Inherited Disorders of Podocyte Function – Martin Pollak
41. Inherited Disorders of the Renal Tubule – Daniel G. Bichet
42. Cystic Diseases of the Kidney – Jared J. Grantham

VII. Hypertension and the Kidney
43. Primary and Secondary Hypertension – Jon D. Blumenfeld
44. Renovascular Hypertension and Ischemic Nephropathy – Stephen C. Textor
45. Hypertension and Kidney Disease in Pregnancy – Ravi Thadani
46. Antihypertensive Drugs – Matthew R. Weir
47. Diuretics – Christopher S. Wilcox

VIII. The Consequences of Renal Failure
48. Pathophysiology of Uremia – Timothy W. Meyer
49. Cardiovascular Apsects of Kidney Disease – Patrick Parfrey
50. Hematologic Aspects of Kidney Disease – Steven Fishbane
51. Endocrine Aspects of Kidney Disease – Ajay K. Singh
52. Neurologic Aspects of Kidney Disease – Allen Arief
53. Renal Osteodystrophies – Sharon Moe

IX. Conservative and Pharmacologic Management of Kidney Disease
54. Diet and Kidney Disease – Gary Curham /Glenn Chertow
55. Specific Pharmacologic Approaches to Renoprotection – Dick DeZeeuw
56. Erythropoietin Therapy in Renal Disease and Renal Failure – John C. Stivelman
57. Vitamin D, Calcimimetics, and Phosphate Binders – William Goodman
58. Prescribing Drugs in Kidney Disease – George R. Aronoff

X. Invasive Therapy of Renal Failure
59. Hemodialysis – Gerald Schulman
60. Peritoneal Dialysis – Peter Blake
61. Intensive Care Nephrology – Bruce Molitoris
62. Plasmapheresis – Bradley M. Denker
63. Extracorporeal Treatment of Poisoning – Ingrid Chang

XI. Renal Transplantation
64. Immunobiology – Mohamed Sayegh
65. Donor and Recipient Issues – Bertram Kaiske
66. Clinical Management – Colm C. Magee

XII. Frontiers in Nephrology
67. Attaining Immunologic Tolerance – Mohamed Sayegh
68. Xenotransplantation – David Sachs
69. Tissue Engineering and Regeneration – Marc Hammerman
70. Stem Cells in Renal Biology and Medicine – Karl L. Skorecki
71. Genomics and Protemics in Nephrology – Joseph V. Bonventre

-Description-

This revised 8th Edition continues to provide comprehensive, exhaustive, and authoritative coverage of nephrology—both underlying basic science and pathophysiology, and diagnosis and management of renal diseases and related conditions.

-Key Features-

Coverage of the complete breadth of the specialty broadens your knowledge base.
A discussion on the basic science that underpins clinical nephrology prepares you for certification or recertification.
A comprehensive selection of the most important sources in nephrology expands your reference needs.
Full-color high-quality photographs, as well as abundant and carefully chosen figures, algorithms, and tables add to your comprehension of the material.
A visually aided, logical organization gives you access to the information you need quickly.

-New to this Edition-

Fourteen brand-new chapters, including Epidemiology of Kidney Disease · Risk Factors and Kidney Disease · Nephron Endowment · Interventional Nephrology · Plasmapheresis · Xenotransplantation · Stem Cells in Renal Biology and Medicine · Gender and Kidney Disease · Inherited Disease of Podocyte Function · Endocrine Aspects of Kidney Disease · Vitamin D, Calcimimetics, and Phosphate Binders · Attaining Immunologic Tolerance · Tissue Engineering and Regeneration · and Genomics and Proteomics in Nephrology enhance your clinical acumen.
Two brand-new sections, Epidemiology and Risk Factors in Kidney Disease and Frontiers in Kidney Disease, including topics such as stem cell and genomics keep you up to date on the latest in the field.