Table of Contents
1 Epidemiology of brain cancer 3
2 Translational applications of molecular biology in neuro-oncology 17
3 Presentation and approach to patient 37
4 Neuroimaging 53
5 Neuropathology 81
6 Surgical management 121
7 Principles of radiotherapy and radiosurgery 143
8 Principles of chemotherapy 163
9 Supportive care 183
10 Neuropsychological issues 201
11 Clinical trial design in neuro-oncology 217
12 The phakomatoses 233
13 High-grade astrocytomas 259
14 Low-grade astrocytomas 289
15 Oligodendroglioma and mixed gliomas 311
16 Brainstem gliomas 333
17 Primacy central nervous system lymphoma 343
18 Primary meningeal neoplasms 369
19 Pituitary adenomas and sellar lesions : multidisciplinary management 381
20 Primitive neuroectodermal tumors 415
21 Ependymomas and intraventricular tumors 431
22 Primary tumors of the cranial nerves and skull base 447
23 Intracranial germ cell tumors 481
24 Primary spinal tumors 501
25 Spinal root and peripheral nerve tumors 533
26 The management of brain metastases 553
27 Spinal metastases 581
28 Leptomeningeal metastases and dural/skull metastases 607
29 Cancer metastasis to the peripheral nervous system 629
30 Paraneoplasia 649
31 Neurologic complications of chemotherapy and biologic therapies 679
32 Neurologic complications of radiation therapy 711
Key Features
1. Comprehensive coverage of all primary and metastatic tumors.
2. Consistent approach to diagnosis and treatment.
3. Replete with examples of sophisticated imaging studies to aid in
diagnosis