Section 1. Neurobiology of pain
1. Peripheral mechanisms of cutaneous nociception
2. Cellular and molecular properties of primary afferent neurons
3. Inflammatory mediators and modulators of pain
4. Neuroanatomical substrates of spinal nociception
5. Plasticity and pain: role of the dorsal horn
6. Representation of pain in the brain
7. Central nervous system mechanisms of pain modulation
8. Development of pain pathways and mechanisms
9. The genetics of pain
10. Animal models of pain
11. Ascending projection systems
12. Autonomic-endocrine-immune interactions in acute and chronic pain
13. Itch
Section 2. Assessment and psychology of pain
14. Emotions and psychobiology
15. Cognitive and learning aspects
16. Psychiatric disorders and pain
17. Studies of pain in human subjects
18. Pain assessment in adult patients
19. Measurement and assessment of paediatric pain
20. Assessment of pain beliefs, coping, and function
21. Hypnotic analgesia
22. The cognitive-behavioural approach to pain management
23. Pain, opiates and addiction
24. Placebo analgesia
Section 3. Pharmacology and Treatment of Pain
25. Central pharmacology of nociceptive transmission
26. Methods of therapeutic trials
27. Opiates: basic mechanisms
28. Opioids: clinical use
29. Antipyretic analgesics: basic aspects
30. NSAIDs and Coxibs: clinical use
31. Antidepressant analgesics: a systematic review and comparative
study
32. Anticonvulsant medications in neuropathic pain
33. Local anaesthetic blocks and epidurals
34. Cannabinoids
35. Analgesic drugs in development
36. Supratentorial neurosurgery for the treatment of pain
37. Spinal cord and brain stimulation
38. Transcutaneous electrical nerve stimulation and acupuncture
39. Peripheral and central nervous system surgery for pain
40. Physiotherapy and pain
Section 4. Clinical states: Deep somatic tissue
41. Basic mechanisms of deep somatic pain
42. Postoperative pain and its management
43. Osteoarthritis and rheumatoid arthritis
44. Myofascial pain and fibromyalgia syndrome
45. Surgical treatment for back and neck pain
46. Low back pain
47. Repetitive strain injury
Section 6. Clinical States: Headache and facial pain
53. Acute and chronic dental and orofacial pain
54. Headache
55. Primary neurovasuclar headache
56. Tension-type headache
57. Pain in and around the eye
Section 7. Clinical states: Neuropathic pain
58. Response of nerves to injury in relation to neuropathic pain
59. Mechanisms of experimental neuropathic pain: integration from
animal models
60. Central consequences of peripheral nerve damage
61. Phantom limb
62. Painful peripheral neuropathies
63. Trigeminal and glossopharyngeal neuralgia
64. Complex regional pain syndromes
65. Root disorders and arachnoiditis
66. Pain following spinal cord injury
67. Central pain
68. Pharmacological therapy for neuropathic pain
Section 8. Clinical states: Cancer pain
69. Cancer pain: causes, consequences and therapeutic opportunities
70. The assessment of cancer pain
71. Analgesic therapy and palliative care in children
72. Cancer pain: treatment overview
73. Pain control in the care of the dying
Section 9. Clinical States: Special cases
74. Pain in the elderly
75. Sex and gender differences in pain and its relief
76. Epidemiology of pain
Index
Description
Now available as a multimedia e-dition, the new 5th Edition of Wall
and Melzack¡¯s Textbook of Pain, revised under new editorial
leadership, and with a host of new, multidisciplinary international
contributors covers virtually every aspect of pain. Read all the
latest about the neurophysiology, psychology, and assessment of every
type of pain syndrome. Describes today's full range of pharmacologic,
surgical, electrostimulative, physiotherapeutic, and psychological
management options. The e-dition offers the book plus a website that
is continuously updated for the life of the edition. All drug
information is linked to Mosby's Drug Consult, all references are
linked to PubMed, and all illustrations and tables can be downloaded
into PowerPoint slides for presentations.
Key Features
*Covers all aspects of the physiology, psychology, assessment, and
management of pain.
*Features contributions from a "who's who" of authorities in pain
medicine, ensuring that the book is the most current, reliable, and
complete core reference in the field.
New to this Edition
*Features the expertise of two highly respected new editors—Stephen
McMahon, PhD and Martin Koltzenburg, MD, PhD—as well as many new
contributors, for a completely fresh look at the subject.
*Uses a new, consistent format to present therapeutic options in an
easy-to-review manner.
*Provides increased coverage of anesthetic techniques.
*Incorporates the most recent pharmacologic developments involving
drug categories such as anticonvulsants, antidepressants, muscle
relaxants, and cannabinoids.
*Several new chapters, including the one on addiction to pain
medication, clinical trials, and evidence-based medicine in pain,
extended headache section (1 chapter in 4/e vs. 4 chapters in 5/e).
*Offers many new illustrations to provide a colorful and graphic
representation of important concepts.
*Reflects all of the changes that have taken place in this rapidly
moving field.