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I. COMMON PROBLEMS

1. Sudden Deterioration of Neurological Status
2. Agitation/Delirium
3. Management of Acute Pain in the ICU
4. Fever and hypothermia
5. Very High Systemic Arterial Blood Pressure
6. Low systemic arterial blood pressure
7. Tachycardia and bradycardia
8. Arterial hypoxemia
9. Acute Respiratory Failure
10. Polyuria
11. Oliguria and anuria
12. Disturbances of acid-base balance
13. Hypernatremia and hyponatremia
14. Hyperkalemia and hypokalemia
15. Hyperphosphatemia and hypophosphatemia
16. Hypomagnesemia
17. Hypercalcemia and hypocalcemia
18. Hypoglycemia
19. Anemia In Critical Illness
20. Thrombocytopenia
21. Coagulopathy
22. Jaundice
23. The Management of Gastrointestinal Bleeding
24. Ileus
25. Diarrhea
26. Rashes
27. Chest Pain

II. BASIC SCIENCE
28. Regulation of Gene Expression
29. The Neutrophil: Balancing Antimicrobial Effectiveness and
Potential for Damage to the Host
30. Macrophage Function
31. Endothelial Function
32. Lung Epithelial Function
33. Lymphocyte Function After Injury
34. Coagulation
35. Complement
36. Pathophysiology of Sepsis and Multiple Organ Dysfunction
37. Mitochondrial Function and Cytopathic Hypoxia
38. Oxidative Lung Injury
39. Apoptosis
40. Cellular Signaling
41. Receptor Physiology
42. Prostaglandins, Thromboxanes, Leukotrines and Other Products of
Arachidonic Acid
43. Nitric oxide
44. Carbon monoxide and HO-1
45. Molecular and Biochemical Monitoring in the ICU
46. Genetics of Critical Illness

III. CENTRAL NERVOUS SYSTEM
47. Advanced Bedside Neuromonitoring
48. Neuroimaging
49. Critical Neuropathophysiology
50. Mechanisms of Neuronal Death
51. Cardiopulmonary Cerebral Resuscitation
52. Coma
53. Intensive Care After Neurosurgery
54. Non-Traumatic Intracerebral and Subarachnoid Hemorrhage
55. Stroke
56. Traumatic Brain Injury
57. Spinal Cord Injury
58. Seizures in the Critically

Ill 59. Neuromuscular Disorders in the ICU
60. Key Issues in Pediatric Neurointensive Care

IV. RESPIRATORY DISORDERS
61. Bedside Monitoring of Pulmonary Function in the Critically Ill
62. Principles of Gas Exchange
63. Arterial Blood Gas Interpretation
64. Mechanics of the Respiratory System/ Respiratory Muscle Function
65. Heart-Lung Interaction
66. Controlled Mechanical Ventilation
67. Patient-ventilator interaction
68. Weaning from Mechanical Ventilation
69. Noninvasive Ventilation
70. High Frequency Ventilation
71. Extracorporeal Life Support
72. Adjunctive Respiratory Therapy
73. Fiberoptic Bronchoscopy in the ICU
74. Indications for and Management of Tracheostomy
75. Hyperbaric Oxygen in Critical Care
76. Imaging of the Chest in ICU

V. SPECIFIC RESPIRATORY PROBLEMS
77. Acute Lung Injury and Acute Respiratory Distress Syndrome
78. Aspiration Pneumonitis and Pneumonia
79. Severe Asthma Exacerbation
80. COPD
81. Pulmonary Embolism
82. Other Embolic Syndromes (Air, Fat, Amniotic Fluid)
83. Pulmonary Hypertension
84. Life Threatening Hemoptysis
85. Pleural Disease and Pneumothorax
86. Community Acquired Pneumonia
87. Nosocomial Pneumonia
88. Pulmonary Infections in the Immunocompromised Patient
89. Lung Transplantation
90. Burns and Inhalation Injury
91. Drowning
92. Acute Respiratory Failure in Pregnancy
93. Acute Parenchymal Disease in Infants and Children
94. Pulmonary Edema

VI. CARDIOVASCULAR DISORDERS
95. Non-Invasive and Invasive Cardiovascular Monitoring
96. Acute Coronary Syndromes
97. Acute Myocardial Infarction
98. Invasive Cardiac Procedures
99. Supraventricular Arrhythmias
100. Ventricular Arrhythmias
101. Conduction Disturbances and Cardiac Pacemakers/Defibrillators
102. Sudden Cardiac Death - Implantable Defibrillators
103. Severe Heart Failure
104. Myocarditis and Acute Myopathies
105. Congenital and Acquired Heart Disease in Children
106. Pericardial Diseases
107. Emergent Valvular Disorders
108. Infectious Endocarditis
109. Cardiac Surgery: Indications and Complications
110. Pathophysiology and Classification of Shock States
111. Resuscitation from Circulatory Shock
112. Inotropic Therapy in the Critically Ill
113. Mechanical Support in Cardiogenic Shock
114. Peripheral Arteriopathies Including Embolism
115. Thromboembolic Disease

VII. HEPATIC DISORDERS, GASTROINTESTINAL DISORDERS, AND NUTRITIONAL
SUPPORT
116. Critical Care Nutrition
117. Ascites
118. Portal hypertension
119. Gastrointestinal hemorrhage
120. Hepatorenal Syndrome
121. Hepatopulmonary syndrome
122. Hepatic encephalopathy
123. Fulminant hepatic failure, including acetominophen toxicity
124. Calculous and acalculous cholecystitis
125. Acute pancreatitis
126. Peritonitis and intra-abdominal abscess
127. Ileus and mechanical bowel obstruction
128. Toxic megacolon and Ogilvie's syndrome
129. Diarrhea
130. Nutritional Issues in Children

VIII. RENAL AND ELECTROLYTE DISORDERS
131. Clinical Assessment of Renal Function
132. Metabolic Acidosis and Alkalosis
133. Disorders of Water Balance
134. Disorders of Plasma Potassium Concentration
135. Disorders of Calcium and Magnesium Metabolism
136. Acute Renal Failure
137. Renal Replacement Therapy in the ICU
138. Drug Dosing in the Patient with Renal Failure
139. Hypertensive Urgencies and Crisis
140. Urinary Tract Obstruction
141. Contrast Dye-induced Nephropathy
142. Glomerulonephritis and Interstitial Nephritis in the ICU
143. Fluid and Electrolytes in Children

IX. INFECTIOUS DISEASES
144. Antimicrobials in Chemotherapy Strategy
145. Beta-lactam Drugs Used in Critical Care
146. Aminoglycosides
147. Fluoroquinolones
148. Macrolides
149. Agents with Primary Activity Against Gram-positive Bacteria
150. Metronidazole and other Antibiotics for Anaerobic Infections
151. Prevention and Control of Nosocomial Infection in the ICU
152. Vascular Catheter Related Infections
153. Septic Shock
154. Sepsis and Multiple Organ System Failure in Children
155. Acute Bacteremias
156. Infections of the Urogenital Tract
157. Central Nervous System Infections
158. Infections of Skin, Muscle, and Soft Tissue
159. Intraabdominal and gastrointestinal Infections
160. Head and Neck Infections
161. Care of the Patient with Human Immunodeficiency Virus
162. Infections in the Immunocompromised Patient
163. Infectious Endocarditis
164. Fungal Infections
165. Tuberculosis
166. Malaria
167. Rickettsial Diseases
168. Acute Viral Syndromes
169. Clostridium difficile colitis: prevention and management
170. Tetanus
171. Botulism
172. Dengue Hemorrhagic Fever and Dengue Shock Syndrome

X. HEMATOLOGIC AND ONCOLOGIC
173. Management of Anemia
174. Blood Component Therapies
175. Management of Leucopenia
176. Prophylaxis of Thrombo-embolic Disease
177. Hematologic Malignancies
178. The Bone Marrow Transplant Patient
179. Adverse Effects of Cancer Therapies
180. Hematology and Oncology in Children

XI. ENDOCRINE DISORDERS
181. Hyperglycemic Comas
182. Hyperglycemia and Blood Glucose Control in the ICU
183. Adrenal Insufficiency
184. Thyroid Gland Disorders
185. Diabetes Insipidus
186. Endocrine and Metabolic Crises in Children

XII. THE OBSTETRIC PATIENT
187. Cardiovascular and endocrinological changes associated with the
pregnant state
188. Hypertensive disorders of pregnancy
189. Peripartum hemorrhage
190. Trauma in the gravid patient

XIII. PHARMACOLOGY AND TOXICOLOGY
191. General principles of pharmokinetics and pharmacodynamics
192. Poisoning: Overview of Approaches for Evaluation and Treatment
193. Ethanol, Methanol, and Ethylene Glycol
194. Anticonvulsants
195. Calcium channel antagonists
196. Tricyclic and SSRI anti-depressants
197. Clinical Use of Immunosuppressants
198. Digitalis
199. Heavy metals
200. Hydrocarbons
201. Lithium
202. Local anesthetics
203. Theophylline and other methyl xanthines
204. Neuroleptic agents
205. Nonsteroidal anti-inflammatory agents
206. Opioids
207. Pesticides and herbicides
208. Sedatives and hypnotics
209. Toxic inhalations
210. Pharmacoeconomics

XIV. PROCEDURES
211. Airway management and endotracheal intubation
212. Bedside ultrasonography
213. Central venous catheterization
214. Arterial Cannulization and Invasive Blood Pressure Measurement
215. Bedside pulmonary arterial catheterization
216. Cardioversion and defibrillation
217. Transcutaneous & Transvenous Cardiac Pacing
218. Pericardiocentesis
219. Paracentesis and diagnostic peritoneal lavage
220. Thoracentesis
221. Intra-aortic balloon counterpulsation
222. Chest Tube Placement, Care, and Removal
223. Fiberoptic bronchoscopy
224. Bronchoalveolar lavage and Bronchial brushing
225. Percutaneous tracheostomy
226. Balloon tamponade for esophageal or gastric variceal bleeding
227. Placement of feeding tubes
228. Lumbar puncture
229. Jugular Venous and Brain Tissue Oxygen Tension Monitoring
230. Intracranial pressure monitoring
231. Indirect calorimetry and metabolic monitoring
232. Cannulation for extracorporeal membrane oxygenation
233. Bedside Laparoscopy in the ICU

XV. SURGERY AND TRAUMA
235. Mediastinitis
236. Epistaxis
237. Management of the Postoperative Cardiac Surgical Patient
238. Management of patients after heart, heart-lung or lung
transplantation
239. Management of patients after kidney, kidney-pancreas, or
pancreas transplantation
240. Management of patients after orthotopic liver transplantation
241. Intestinal and Multiple Organ Transplantation
242. Ventricular assist devices
243. Aortic dissection
244. Mesenteric ischemia
245. Abdominal compartment syndrome
246. Thrombolytics
247. Atheroembolization
248. Pressure sores
249. Management of pain, anxiety and delerium
250. Resuscitation of hypovolemic shock
251. Burns
252. Thoracic trauma
253. Abdominal trauma
254. Pelvic and major long bone fractures
255. Pediatric Trauma
256. Management of the Brain Dead Organ Donor
257. Non-Heartbeating Organ Donation

XVI. ETHICAL AND END OF LIFE ISSUES
258. Beyond Technology: Caring for the Critically Ill Patient
259. Resource Allocation in the ICU
260. Basic Ethical Principles in the ICU
261. Ethical Issues in Pediatric Critical Care
262. End of Life in the ICU
263. Determination of Brain Death

XVII. ORGANIZATION, MANAGEMENT, AND EDUCATION
264. Inter- and Intra-Hospital Transport
265. Key Issues in Critical Care Nursing
266. Disaster Medicine for the ICU Physician
267. Building Bedside Collaborative Practice
268. The Pursuit of Performance Excellence
269. Severity of Illness and Outcome Prediction
270. Evaluating Pediatric Critical Care
271. Evidence Based Critical Care
272. Teaching Critical Care