Table of Contents
Contributors
Foreword
Preface
Acknowledgments
Sect. I Environmental and Occupational Disease
1 The Discipline of Environmental and Occupational Medicine 3
2 Recognition and Evaluation of Occupational and Environmental Health Problems 11
3 The Role of Surveillance in Occupational Health 19
4 The Occupational and Environmental History and Examination 31
5 Epidemiology of Occupational Diseases 39
6 Occupational Biostatistics 57
7 Impairment, Disability, and Functional Capacity 67
8 Occupational Health and Managed Care into the 21st Century 79
Mechanisms of Occupational Disease Injury
9 The Immune System and the Environment 87
10 Molecular Biology 113
11 Environmental Carcinogenesis 137
12 Molecular Carcinogenesis 155
13 p53 Tumor Suppressor Gene: At the Crossroads of Molecular Carcinogenesis and Molecular Epidemiology of Human Cancer 167
14 Biologic Markers 177
15 Environmental Mutagenesis 187
16 Experimental and Computational Strategies for the Rapid Identification of Environmental Carcinogens 197
17 Genetic Susceptibility 209
18 Occupational Exposures and Effects on Male and Female Reproduction 223
Organ System: Lung
19 Particle Deposition and Pulmonary Defense Mechanisms 245
20 Pulmonary Function Testing 261
21 Chest Radiography for Assessment of the Pneumoconioses 293
22 Molecular Mechanisms of Particle-Induced Lung Disease 305
23 Fiber Analysis 335
24 Asbestos-Related Diseases 349
25 Animal Models of Malignant Mesothelioma 377
26 Asbestos in Public Buildings 387
27 Man-Made Vitreous Fibers, Vermiculite, and Zeolite 397
28 Respiratory Disease in Coal Miners 413
29 Silicosis 435
30 Byssinosis and Other Diseases of Textile Workers 449
31 Hypersensitivity Pneumonitis 457
32 Inhalation Fever 467
33 Occupational and Environmental Asthma 481
34 Inflammatory Mechanisms of Asthma 525
35 Respiratory Effects of Isocyanates 537
36 Agricultural Dust-Induced Lung Disease 565
37 Occupational Exposures as a Cause of Chronic Airways Disease 573
38 Silicates and Benign Pneumoconioses 587
39 Ozone 601
40 Nitrogen Dioxide/Nitric Oxide 617
41 Sulfur Dioxide and Sulfuric Acid Aerosols 631
42 Respiratory Tract Irritants 641
43 Simple Asphyxiants 651
44 Chemical Asphyxiants 657
Other Organ Systems
45 Rhinitis and Sinusitis 667
46 Occupational Skin Disease 675
47 Toxic Peripheral Neuropathy 697
48 Human Behavioral Neurotoxicology: Workplace and Community Assessments 709
49 Occupational Heart Disease 733
50 Occupational Eye Disorders 743
51 Occupational Infections 755
52 HIV in the Workplace 775
53 The Occupational Risk of Tuberculosis Care 797
54 Endocrine Disruption from Environmental Toxicants 807
55 Hematologic Effects of Occupational Hazards 817
56 Toxic Liver Disorders 831
57 Environmental and Occupational Causes of Toxic Injury to the Kidneys and Urinary Tract 843
58 Bladder Carcinogens 857
59 Alcohol and Drug Abuse in Industry 865
60 Psychiatric Syndromes Common to the Workplace 881
61 Multiple Chemical Sensitivity 891
62 Psychological Job Stress 905
63 Epidemiology of Occupational Injury 915
64 Occupational Safety and Human Factors 923
65 Work-Related Musculoskeletal Disorders Excluding Back Pain 937
66 Nonspecific Low Back Pain 947
67 Work-Related Disorders of the Neck and Upper Extremity 959
Sect. II Environmental and Occupational Exposures
Metals
68 Occupational and Environmental Exposure to Lead 973
69 Mercury 997
70 Cadmium 1005
71 Arsenic 1011
72 Beryllium Disease 1021
73 Hard Metal Disease 1037
74 Chromium Compounds 1045
75 Nickel Toxicity and Carcinogenesis 1057
76 Pulmonary and Neurologic Effects of Aluminum 1065
77 Metal Compounds and Rare Earths 1075
Organic Chemicals
78 Organic Solvents 1091
79 Benzene 1109
80 Formaldehyde 1115
81 Styrene and Butadiene 1129
82 Ethylene Oxide 1145
83 Pesticides 1157
84 Health Effects of Phenoxy Herbicides and Agent Orange 1173
85 Dioxins and Related Compounds 1185
86 Pentachlorophenol and Tetrachlorophenol 1199
87 Polychlorinated Biphenyls 1205
88 Trimellitic Anhydride 1215
89 Carbon Disulfide 1221
90 N-Nitrosamines 1227
91 The Bhopal Disaster 1239
92 Health Effects of Dibromochloropropane 1245
93 Vinyl Chloride and Polyvinyl Chloride 1251
94 Polycyclic Aromatic Hydrocarbons 1261
95 Petroleum Refining Industry 1269
96 Occupational Hazards in the Microelectronics Industry 1277
Radiation
97 Ionizing Radiation 1293
98 Diseases of Uranium Miners and Other Underground Miners Exposed to Radon 1307
99 Nonionizing Radiation 1317
Physical Environment
100 Occupational Health Aspects of Work with Video Display Terminals 1333
101 Occupational Exposure to Noise 1345
102 Dysbarism 1359
103 High-Altitude Illnesses 1377
104 Hot and Cold Work Environments 1389
105 Occupational Exposure to Vibration 1403
106 Shift Work: Health and Performance Effects 1411
107 Sleep Disorders and Work 1415
108 Ergonomics 1423
109 Biomechanics 1437
110 Firefighters' Health and Safety 1455
111 Occupational Hazards in the Visual and Performing Arts 1465
112 Sick Building Syndrome and Building-Related Illness 1471
Personal and General Environment
113 Cigarette Smoking and Cancer 1479
114 Community Air Pollution 1501
115 Indoor Air Pollution 1523
116 Air Pollution: Human Health Studies 1539
117 Acid Rain 1549
118 Organismic Responses to Contaminated Aquatic Systems: Four Case Histories from the Hudson River 1563
119 Fate and Bioaccumulation of PCBs in Aquatic Environments 1581
120 Persian Gulf War Health Issues 1595
121 Hazardous Waste 1611
122 Biologic and Medical Implications of Global Warming 1625
123 Chlorofluorocarbons and Destruction of the Ozone Layer 1639
Sect. III Control of Environmental and Occupational Diseases and Exposures
124 Environmental Law and the Science of Ecology 1651
125 OSHA and the Regulatory Agencies 1671
126 Economic Issues in Occupational Safety and Health 1681
127 Risk Assessment 1691
128 Workers' Compensation 1709
129 International Occupational and Environmental Health 1715
130 Child Labor 1725
131 Environmental Justice 1731
132 Industrial Hygiene Measurement and Control 1741
133 Respirators 1757
134 The Occupational Health Service 1767
135 On the Ethical Practice of Environmental and Occupational Medicine 1795
136 New Frontiers in Environmental Health Research 1807
Subject Index 1815
Book Description
Now in its updated Fourth Edition, this classic text provides comprehensive coverage of all aspects of occupational and environmental medicine. The book offers accurate, current information on the history, causes, prevention, and treatment of a wide range of environmental and occupational diseases and includes numerous case studies. This edition includes more information on gene-environment interactions. The section on air pollution has been completely reorganized. Other Fourth Edition highlights include expanded coverage of government responses to the field and a new chapter on children's environmental health.
